• 0 Posts
  • 9 Comments
Joined 2 years ago
Cake day: June 20th, 2023
  • Neuromancer49@midwest.socialtoScience Memes@mander.xyz•Homer Simpson irlEnglish
    77·
    2 months ago

    I ran a lot of MRIs for my PhD. I saw somewhere around 100-200 different brains. About 10% of them had abnormalities. Of all the technicians, scientists, and (non-clinical) doctors I spoke with, we all agreed this was a very high rate of discovery. All my friends graduated without seeing anything weird. My advisor liked to joke that I was cursed. Eventually I stopped inviting my friends to do my experiments because I didn’t want to deal with the risk of them having an abnormality - thanks to some combination of HIPAA and medical liability laws, I wasn’t allowed to say anything about it, even if asked point blank. I didn’t like that very much.

    I made one exception, as a friend of mine came in for a study and I saw a golf ball sized cyst in his sinus. He had it surgically removed and he told me he stopped snoring the next day. It felt good to make a difference for him.

    But, I saw one brain similar to the one documented here. It belongs to one of my close friends. It was harrowing. Entire left hemisphere was malformed, the ventricles were way too big and the cortex was way too thin. But the right side of his brain was underdeveloped, maybe the size of a tennis ball.

    The weirdest part, he is 100% normal. In fact, he competed at a high level of college athletics. Normal Cognition, normal motor function, great sense of humor, and a very caring person. Now he has a great job, wife and kid, and we hang out often. But I can’t bring myself to say anything, and every time I see his son I wonder about his brain.

  • Neuromancer49@midwest.socialtoAsklemmy@lemmy.ml•Do you think things will get better?English
    4·
    6 months ago

    Unfortunately there’s a lot of truth in that statement, especially in the case of rare disease. It’s really difficult to convince a company to spend billions to develop a treatment that will only cure 1 in 100,000 people without letting them charge an arm and a leg, and giving them a very long exclusivity deal so they can continue to charge high prices. So much of that cost to develop is due to the dozens of other failed drugs and formulations they tried on their way to success.

    I don’t have a solution for the problem, and I’m always a little suspicious of anyone who claims it’s easy to solve. I think the UK has a decent idea, the NHS basically decides if the cost of a drug will be covered by insurance by comparing the expected benefit and the current cost. If the ratio is too skewed, they refuse to cover the medication. In theory, this should be an incentive for a company to charge less. In practice, it leads to some companies choosing not to market in the UK.

  • Neuromancer49@midwest.socialtoAsklemmy@lemmy.ml•Do you think things will get better?English
    132·
    6 months ago

    Here’s a bit of hope for you, scientists have figured out how to trick the body into producing any protein or antibody they want, through technology like gene therapy and mRNA vaccines. We’re about to cure a lot of diseases that used to be 100% fatal. Diseases that kill kids and adults alike.

    Most things seem to be getting worse these days, but at least we’re making progress in other areas.